Strongyloidiasis 200 mcg/kg as a single dose. Onchocerciasis 150 mcg/kg as a single dose. Most commonly used dose interval in international treatment programs: 12 mth. Retreatment may be considered at 3 mth interval.
Possible cutaneous &/or systemic reactions of varying severity (the Mazzotti reaction) & ophth reactions in patients w/ onchocerciasis. Perform repeated stool exam to document clearance of Strongyloides stercoralis infection in patients w/ strongyloidiasis. May require repeated follow-up & retreatment in patients w/ onchocerciasis. May require repeated courses of therapy in immunocompromised (including HIV-infected) patients. Not to be used during pregnancy. Nursing mothers. Ped patients weighing <15 kg. Elderly.
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